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Effect of beta-1,6-Glucan Inhibitors on the Invasion Process of Candida albicans: Potential Mechanism of Their In Vivo Efficacy
Antimicrobial Agents and Chemotherapy, 08/26/09
Kitamura A et al. – The results of the experiment using an in vitro model of vaginal candidiasis showed that D21–6076 strongly inhibited the invasion process of C. albicans without a significant reduction in its growth in the medium. These evidences suggested that D21–6076 probably exhibited in vivo efficacy against C. albicans by inhibiting its invasion process.
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