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Persson U et al. – Ex ante VBP assessment is a form of risk sharing, which has been used by TLV to speed up reimbursement and dispersion of effective new drugs despite uncertainty in their true cost–effectiveness. Manufacturers are often asked in return to generate additional health economic evidence that will establish cost–effectiveness as part of ex post review. The alternative is to delay the reimbursement approval until satisfactory evidence is available.

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