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Metabolic Syndrome in Women With PCOS
The Female Patient, 07/31/09
Nelson AL – Polycystic ovary syndrome is the most common endocrinopathy in reproductive–aged women. Many women with PCOS also have metabolic syndrome. Blood pressure and weight distribution can be easily gauged during an office visit. Glucose tolerance testing is generally indicated by some combination of family history of diabetes, personal history of gestational diabetes, elevated BMI, or suggestive physical findings. The need for lipid testing may be indicated by an elevated BMI, a strong family history of hyperlipidemia/CVD, or a diagnosis of metabolic syndrome based on other criteria. Diet and exercise remain the most effective long–term therapies. Pharmacologic agents should be reserved for high–risk women and those who fail lifestyle interventions. Importantly, women with PCOS and prediabetes have tight therapeutic targets for control of blood pressure and lipids—ie, the same as for women with overt diabetes.
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