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Paschale MD et al. – As first pregnancies in Italy generally occur later than they did in the past, the majority of women have already recovered from primary infection by the time they reach childbearing age and almost certainly by the time of their first pregnancy. Moreover, in this study 95% of the women had an age between 21 and 40 years while age classes of 20 or less than 20 and over 40 years were under–represented; so this could be a further cause of the lack of difference in seroprevalence.

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