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Inadvertent potential risk of neoadjuvant chemotherapy in cervical cancer
Medical Hypotheses, 06/25/09
Kim K et al. - Randomized clinical trials comparing neoadjuvant chemotherapy (NAC) followed by surgery with initial surgery in cervical cancer reported conflicting results. The authors provided a hypothesis explaining the different outcomes between trials. The empirical data showed that patients who underwent NAC followed by surgery and were classified as low-risk based on pathologic parameters had unexpectedly high recurrence rate.
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