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See Latest ArticlesAltered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene
Proceedings of the National Academy of Sciences of the United States of America, 07/01/09
Atwal GS et al. - This report not only implicates MDM4 as a key regulator of tumorigenesis in the human breast and ovary, but also exploits for the first time evolutionary driven linkage disequilibrium as a means to select SNPs of p53 pathway genes that might be clinically relevant.
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