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See Latest ArticlesEtiology of Down syndrome: Evidence for consistent association among altered meiotic recombination, nondisjunction, and maternal age across populations
American Journal of Medical Genetics, 06/30/09
Ghosh S et al. - The authors observed an association between meiosis I nondisjuncion and recombination in the telomeric 5.1 Mb of chromosome 21. Overall reduction of recombination irrespective of maternal age is also evident in meiosis I cases. This not only provides much needed confirmation of previous results, but it suggests that the genetic etiology underlying the occurrence of trisomy 21 may be similar across human populations.
Subrata Kumar Dey, 07/24/09
| Results of our investigaton proves beyhond doubt that reduced recombination is one of the important cause of nondisjunction during meiosis.However,we intend to continue the investigation with larger sample size and markers. |
Today in Basic Science/Genetics...keeping you current
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Unexplained fetal loss: the fetal side of thrombophilia
Fertility and Sterility, 11/12/09
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers
Human Molecular Genetics, 11/03/09
Genetic Variation in the Progesterone Receptor and Metabolism Pathways and Hormone Therapy in Relation to Breast Cancer Risk
American Journal of Epidemiology, 10/22/09
Today in Menopausal Medicine...keeping you current
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A New Drug in a New Class for Postmenopausal Osteoporosis
The Female Patient, 11/11/09
Effect of Transdermal Teriparatide Administration on Bone Mineral Density in Postmenopausal Women
Journal of Clinical Endocrinology and Metabolism, 11/10/09
Reducing hip fracture risk with risedronate in elderly women with established osteoporosis
Clinical Interventions in Aging, 11/11/09
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