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Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects
Atherosclerosis, 06/03/09
Rajendran S et al. - In PCOS subjects, independent of obesity and associated insulin resistance, profound and reproducible impairment of platelet responsiveness to NO is an additional component of cardiovascular homeostatic disturbance.
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Metformin Reduces Arterial Stiffness and Improves Endothelial Function in Young Women with Polycystic Ovary Syndrome: A Randomized, Placebo-Controlled, Crossover Trial
Journal of Clinical Endocrinology and Metabolism, 12/17/09
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