Ob/Gyn Medical News about POF

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Aetiology of premature ovarian failure
Menopause International, 05/27/09

Vujovic S - Autoimmune ovarian damage is caused by the alteration of T-cell subsets and T-cell-mediated injury, increase of autoantibody producing B-cells and a low number of effector supressor/cytotoxic lymphocyte and a decrease of number and activity of natural killer cells. POF can be associated with other non-endocrine and endocrine diseases. The mutations of AIRE gene are responsible for polyendocrinopathies (APS I–III). As the cause of POF is unknown in the majority of cases and the number of women with POF is increasing, the primary goal of scientific groups worldwide should be focused on the study of the aetiology of POF.

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Array Comparative Genomic Hybridization Profiling Analysis Reveals Deoxyribonucleic Acid Copy Number Variations Associated with Premature Ovarian Failure
Journal of Clinical Endocrinology and Metabolism, 10/29/09 Relevance Score: 85%

Estrogen receptor gene polymorphisms in patients with idiopathic premature ovarian failure
Human Reproduction, 10/28/09 Relevance Score: 80%

In vitro fertilisation (IVF) with donor eggs in post-menopausal women: are there differences in pregnancy outcomes in women with premature ovarian failure (POF) compared with women with physiological age-related menopause
Journal of Assisted Reproduction and Genetics, 10/26/09 Relevance Score: 80%

Disruption of Tsc2 in oocytes leads to overactivation of the entire pool of primordial follicles
Molecular Human Reproduction, 10/21/09 Relevance Score: 80%

FOXL2 mutations lead to different ovarian phenotypes in BPES patients: Case Report
Human Reproduction, 10/13/09 Relevance Score: 80%