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Reduced levels of GH during GnRH analogue treatment in pubertal short girls born small for gestational age (SGA)
Clinical Endocrinology, 05/27/09

Van Der Kaay DCM et al. - Short SGA girls lack the normal increase in GH levels seen in puberty and have reduced IGF-I and IGFBP-3 levels, which might explain their reduced pubertal growth spurt. GnRHa treatment led to a significant reduction in GH levels. Therefore, combining GnRHa treatment with GH treatment might improve adult height of short SGA girls.

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