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Dehydroepiandrosterone sulfate and insulin resistance in patients with polycystic ovary syndrome
Fertility and Sterility, 05/12/09
Azziz R et al. - DHEAS is negatively correlated to insulin resistance in patients with PCOS, and in model ranked just behind other well-established predictors including BMI, WHR, and age. Whether this is due to a direct beneficial effect on insulin action by adrenal androgens such as DHEA, or whether DHEAS simply reflects the circulating levels of hyperinsulinemia, remains to be determined.
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