Ob/Gyn Medical News about late radiation tissue injury;gynecological patients;hyperbaric oxygen therapy

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Hyperbaric oxygen therapy for late radiation tissue injury in gynaecological patients
Supportive Care in Cancer, 03/31/09

Rud AK et al. - In a study to investigate the possible pain reducing effect of hyperbaric oxygen treatment (HBOT) in pts with late radiation tissue injury (LRTI) after radiation for gynaecological malignancy, it was not possible to conclude if gynaecological pts with pelvic pain will benefit from HBOT. Application of HBOT to selected pts may be justified, but further research with adequate sample size, as well as timing of HBOT related to the development of LRTI, is required to establish the optimum pt selection.

Methods

Possible pain reducing effect of HBOT was investigated in 16 pts with LRTI after radiation for gynaecological malignancy.
16 pts were registered prospectively, underwent HBOT for 21 consecutive days, and were followed for a 6-mo period after treatment using the Brief Pain Inventory, Montgomery and Aasberg Depression Rating Scale, as well as registration of global patient scores, analgesic consumption, and magnetic resonance imaging (MRI) findings.

Results

HBOT was shown to have insignificant effect on pain, pain characteristics, daily function, use of analgesics, and MRI-related tissue injury.
50% of pts still reported some or good effect of the treatment.

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