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Pitfalls in Screening Programs for Congenital Hypothyroidism in Premature Newborns
American Journal of Perinatology, 12/12/08
Kugelman A et al. - Screening programs should report thyroid-stimulating hormone (TSH) as well as thyroxine (T4) levels in premature infants, which will allow the treating physicians to be aware of possible abnormality that needs to be followed. Sick premature infants and other populations at risk should undergo a full serum thyroid function evaluation including free T4 and TSH beyond the screening program at discharge or at 30 days of age, whichever comes first. Physicians should use their clinical judgment and experience even in the face of normal newborn thyroid screening test and reevaluate for hypothyroidism when there is a clinical suspicion.
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