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Increased Incidence of Gestational Diabetes in Women Receiving Prophylactic 17alpha-Hydroxyprogesterone Caproate for Prevention of Recurrent Preterm Delivery
Diabetes Care, 09/06/07

Rebarber, A., et al. - Progesterone has a known diabetogenic effect. We sought to determine whether the incidence of gestational diabetes mellitus (GDM) is altered in women receiving weekly 17alpha-hydroxyprogesterone caproate (17P) prophylaxis for the prevention of recurrent preterm birth...Conclusions: The use of 17P for the prevention of recurrent preterm delivery is associated with an increased risk of developing GDM. Early GDM screening is appropriate for women receiving 17P prophylaxis

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