Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans
Kang HJ et al. - The association of SNPs in the p53 pathway with human fertility suggests that p53 regulates the efficiency of human reproduction. These results also provide a plausible explanation for the evolutionary positive selection of some alleles in the p53 pathway and demonstrate the alleles in the p53 pathway as a good example of antagonistic pleiotropy. [more...]
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