Nursing News & Articles

RBP4 is weakly associated with subclinical atherosclerosis

As published in Cardiovascular Diabetology, an elevated retinol-binding protein 4 (RBP4) level was shown to be associated hypertriglyceridemia and coronary artery calcification, but not other cardiometabolic risk factors, such as hypertension, hypercholesterolemia, hyperglycemia, hyperinsulinemia, elevated CRP, and increased CIMT. The study involved 709 postmenopausal women from the Kronos Early Estrogen Prevention Study (KEEPS).

n-3 PUFAs are renoprotective in diabetics

As published in Diabetes Care, n-3 PUFA supplementation (4 g/d x 6 w) in patients with diabetes (n=29) resulted in decreased urine NGAL excretion; there was no effect on urine albumin excretion, serum markers of kidney function, and eGFR. In patients taking RAAS blockers, n-3 PUFA supplementation decreased albumin excretion, NGAL, LFABP, and NAG.

Homocysteine and folate predict CHD and all-cause mortalities

Researchers at the University of Sydney have reported that the highest vs. lowest quartile of homocysteine (HR=2.45) and folate deficiency (HR=1.53), but not vitamin B12 levels, predict CHD mortality. Further hyperhomocysteinaemia (> 15 µmol/L) was reported to be associated with all-cause mortality (HR=1.47).