Children’s Depression Screener is a useful tool
As reported in Psychiatry Research, the Childrens Depression Screener (ChilD-S) has been shown to have a diagnostic accuracy of 0.97 in children with depression and at a cut-off level ≥ 12, the sensitivity and specificity are 0.91 and 0.81, respectively.
KIT mutations associated with poor prognosis in GISTs
Based on a meta-analysis (18 studies; n=1487) reported in the World Journal of Surgical Oncology, KIT mutations in patients with gastrointestinal stromal tumors (GISTs) are associated with larger tumors (> 5 cm), higher mitotic activity (> 5), more frequent recurrences (OR = 2.06), more frequent metastases (OR = 2.77), and worse 3-year overall survival (OR = 0.47) compared to patients with PDGFRA mutations or wild-type.
Cortisol as a biomarker of obstructive sleep apnea
As reported in Pediatric Pulmonology, salivary cortisol has an increased diurnal variation in children with mild or moderate-to-severe obstructive sleep apnea, while no changes in α-amylase were detected.