Molecular genetics of adult grade II gliomas: towards a comprehensive tumor classification system
Journal of Neuro-Oncology, 08/20/2012
Figarella–Branger D et al. – The findings could significantly modify low–grade gliomas (LGG) classification and may represent a new tool to guide patient–tailored therapy. Moreover, immunohistochemical detection of p53, INA and mR132H IDH1 expression could represent an interesting prescreening test to be performed before 1p19q codeletion, IDH1 minor mutation and IDH2 mutation detection.