Risk Factors for and Outcomes of Acute Kidney Injury in Neonates Undergoing Complex Cardiac Surgery
The Journal of Pediatrics, 08/10/2012
Morgan CJ et al. – Neonatal cardiac surgery–associated acute kidney injury (CS–AKI) is common and independently predicts important clinical outcomes, including mortality. Many risk factors are similar to those in older children, but some are unique to neonates. The observation that lower baseline SCr predicts CS–AKI merits further study. The AKIN definition, based on preoperative serum creatinine (SCr) value, is a reasonable method for defining CS–AKI in neonates. Many previous studies of CS–AKI have excluded neonates; the authors suggest that future intervention studies on approaches to reducing CS–AKI incidence and improving outcomes should include neonates.