An overview of the pharmacokinetics, efficacy and safety of liraglutide
Diabetes Research and Clinical Practice, 08/08/2012
Bode B – Liraglutide is an effective and well tolerated option for the treatment of type 2 diabetes.Methods
- Data are presented from the pharmacokinetics/pharmacodynamics studies of liraglutide and from nine published phase 3 studies, including the six Liraglutide Effect and Action in Diabetes (LEAD) studies.
- Liraglutide is effective at improving indices of glycemic control, and has a good tolerability and safety profile.
- Beneficial effects on weight (mean reduction of 1–3.4kg) and blood pressure (systolic blood pressure decreased by 2.1–6.7mmHg) are also observed.