Short-term continuous glucose monitoring: effects on glucose and treatment satisfaction in patients with type 1 diabetes mellitus; a randomized controlled trial
International Journal of Clinical Practice,
Langeland LBL et al. – The frequency of severe hypoglycaemic episodes, treatment satisfaction and health status was also equal between the two interventions. No adverse events were observed.Methods
- Thirty patients suffering from DM1 for more than three years and treated with either insulin pumps or multiple daily insulin injections, were included in a randomised controlled cross–over trial.
- They were Caucasians of both genders, between 18 and 50 years, and had moderately well controlled diabetes.
- The participants performed either ICFM or CGM for 4 weeks, followed by an 8 week's observation period.
- Thereafter they were crossed over to the opposite intervention.
- HbA1c, hypoglycaemic episodes, treatment satisfaction and health status were assessed at all meetings, although HbA1c was the primary endpoint.
- At inclusion mean HbA1c was 7.8 ± 0.9 %.
- The mean change in HbA1c was –0.2 ± 0.1% and –0.2 ± 0.1% for the CGM and the ICFM periods, accordingly (p = 0.91).
- The mean changes in HbA1c during the combined treatment and observation periods were –0.1 ± 0.1% and –0.2 ± 0.1% for the CGM and the ICFM period, accordingly (p = 0.86).
- The frequency of severe hypoglycaemic episodes, treatment satisfaction and health status was also equal between the two interventions.
- No adverse events were observed.