Narrow-band imaging cystoscopy in non-muscle-invasive bladder cancer: a prospective comparison to the standard approach
Therapeutic Advances in Urology, 07/18/2012
Geavlete B et al. – Narrow–band imaging cystoscopy represents a valuable diagnostic alternative in patients with non–muscle–invasive bladder cancer, with significant improvement in tumor visual accuracy as well as detection. This approach provides a substantial improvement to bladder cancer therapeutic management.Methods
- A total of 95 NMIBC-suspected consecutive cases were enrolled.
- The inclusion criteria were hematuria, positive urinary cytology or ultrasound suspicion of bladder tumors.
- All patients underwent WLC and NBI cystoscopy.
- Standard resection was performed for all lesions visible in white light and NBI transurethral resection of bladder tumors for only NBI-observed tumors.
- The overall detection rates of NMIBC and carcinoma in situ (CIS) were significantly improved for NBI (96.2% versus 87.2% and 100% versus 66.7% respectively).
- Also, NBI cystoscopy showed significantly superior detection for CIS, pTa and overall tumors (95.2% versus 61.9%, 93.9% versus 85.2% and 94.8% versus 83.9% respectively).
- Additional tumors were diagnosed by NBI in a significant proportion of patients with CIS, pTa, pT1 and NMIBC (55.5% versus 11.1%, 26.5% versus 10.2%, 30% versus 10% and 30.8% versus 10.3%).
- Postoperative treatment was significantly improved due to NBI results (16.7% versus 5.1%).