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Risk factors affecting progressive collapse of acute osteoporotic spinal fractures
Osteoporosis International, 07/05/2012
Ha KY et al. – A thoracolumbar fracture, a mid–portion type fracture, and involvement of the vertebral posterior wall are relative risk factors for progressive collapse following acute osteoporotic spinal fractures (OSF). More attention should be paid to patients with OSF and these risk factors during conservative management.
Methods- In total, 100 patients with acute OSF were prospectively enrolled at a single institute.
- Five pathological fractures were excluded.
- Twelve patients dropped out of the study because of conversion to surgical treatment during follow–up.
- Eight patients were excluded as follow–up losses.
- Thus, 75 patients were analyzed. Clinical data and radiological data were recorded and analyzed.
- As a definition of progressive OSF, height loss ≥15 %, kyphotic angle ≥10°, and the occurrence of an intravertebral cleft sign at the 6–month follow–up compared to the initial values were adopted.
- Correlation analysis and multiple logistic regression analyses were performed to elucidate the related clinical or radiological factors for progressive OSF.
- The occurrence of intravertebral cleft was not related to any significant differences in the clinical results and was only related to the fracture level in the regression analysis.
- A ≥15 % increase in height loss and a ≥10° increase in kyphotic angle were related to worse clinical results.
- Mid–portion type fractures and involvement of the posterior wall were significant risk factors with relatively high odds ratios for progressive OSF under these criteria.
