Intrapatient Cetuximab Dose Escalation in Metastatic Colorectal Cancer According to the Grade of Early Skin Reactions
Journal of Clinical Oncology, 07/05/2012
Van Cutsem E et al. – Cetuximab serum concentrations increased predictably with dose. Higher dose levels were well tolerated. The possible indication for improved efficacy in the dose–escalation group warrants further investigation.