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Adenovirus Respiratory Infections in Hospitalized Children: Clinical Findings in Relation to Species and Serotypes
The Pediatric Infectious Disease Journal, 06/22/2012
Tabain I et al. – In this study, the most common isolated serotype was adenovirus (ADV) type 2. Most affected children were younger than 3 years. ADV infections in young children can present with prolonged fever, leukocytosis and significantly elevated C–reactive protein and erythrocyte sedimentation rate, mimicking bacterial infections.
Methods- During the 3-year period from January 2006 to November 2008, 135 children (<10 years of age) with ADV respiratory infection, based on virus isolation, were treated at 2 hospitals in Zagreb.
- Demographics, clinical presentations and laboratory findings were evaluated.
- Of the 135 ADV isolates, 77 (57.0%) were type 2, followed by 26 (19.3%) of type 1, 15 (11.1%) isolates of type 3, 2 (1.5%) of type 6 and only 1 (0.7%) was type 7.
- Male-to-female ratio was 3.2:1 (103 boys and 32 girls).
- The most common symptoms were fever (98%), rhinorrhea (89%) and cough (71%).
- Serum C-reactive protein was >40 mg/L in 74 patients (56%). The erythrocyte sedimentation rate was >30 mm/h in 91 (71%) of the 127 patients tested.
