Moyamoya Disorder in the United States
Starke RM et al. – Patients admitted to US hospitals diagnosed with moyamoya disorder were more commonly female and white, and both adults and children were more likely to be diagnosed with ischemic vs hemorrhagic stroke. Over time, there was an increase in diagnosis, associated ischemic stroke, and treatment with extracranial–intracranial bypass.Methods
- A comprehensive assessment of the Nationwide Inpatient Sample of the Healthcare Cost and Utilization Project (2002-2008) was performed.
- Patient demographics, comorbidities, procedures, and outcomes were analyzed.
- There were 2280 admissions for moyamoya disorder with a predicted national estimate of 11163 admissions (0.57/100000 persons/y).
- Over time, there was a significant increase in diagnosis and associated ischemic strokes.
- Females (72%) were affected more than males (28%).
- Demographics included white (49%), black (24%), Hispanic (11%), Asian (11%), and other (3.3%).
- Mean age at presentation was 31.6 ± 18.0.
- Children were significantly more likely to be diagnosed with ischemic phenomena (16.4%) than hemorrhage (3.3%), as were adults (18.8% vs 11.0%).
- Status at discharge was largely routine (74.8%) vs short-term hospital (3%), home health care (7%), transfer to another hospital (12%), or in-hospital death in 2.3%.