Effect of Clarithromycin in Inflammatory Markers of Patients with Ventilator-Associated Pneumonia and Sepsis Caused by Gram-Negative Bacteria: Results from a Randomized Clinical Study
Antimicrobial Agents and Chemotherapy, 06/21/2012
Spyridaki A et al. – The results suggest that the administration of clarithromycin restored the balance between proinflammatory versus anti–inflammatory mediators in patients with sepsis; this was accompanied by more efficient antigen presentation and increased apoptosis. These effects render new perspectives for the immunotherapy of sepsis.