Dietary-resistant starch and glucose metabolism
Current Opinion in Clinical Nutrition & Metabolic Care, 06/26/2012
Robertson MD – Resistant starch may have a role in glycaemic control in healthy individuals and those with type 2 diabetes; however, there are limited interventional trials in humans to support this. There are no data concerning resistant starch feeding in human diabetes and as such no health recommendation can be made.Methods
- Recent findings in models suggest that resistant starch is beneficial for both body weight regulation and glycaemic control.
- The purpose of this review is to summarize the current evidence and recommendations in humans.
- When resistant starch replaces available carbohydrate in a meal, postprandial glycaemia is reduced.
- There are some data to suggest that resistant starch may affect glycaemia even when the available carbohydrate portion remains constant; however, there is inconsistency in the literature.
- Recent model data suggest that chronic resistant starch feeding upregulates glucagon-like peptide 1 expression in the large bowel with concomitant increases in neuropeptide expression in the hypothalamus, combining to result in weight loss and improvements in glycaemic control.