Low body temperature associated with severe ischemic stroke within 6 hours of onset: The Bergen NORSTROKE Study

Vascular Health and Risk Management, 06/04/2012

Kvistad CE et al. – The study suggests that low body temperature within 6 hours of symptom onset is associated with severe ischemic stroke. This is in support of the hypothesis, although other contributing mechanisms cannot be excluded.

Methods

  • In this prospective study, patients (n = 516) exhibiting ischemic stroke with symptom onset within 6 hours were included.
  • Body temperature and National Institute of Health Stroke Scale (NIHSS) score were registered on admission.
  • Because low body temperature on admission may be secondary to immobilization due to large stroke, separate analyses were performed on patients with cerebral hemorrhage admitted within 6 hours (n = 85).

Results

  • Linear regression showed that low body temperature on admission was independently associated with a high NIHSS score within 6 hours of stroke onset in patients with ischemic stroke (P < 0.001).
  • The association persisted when NIHSS was measured at 24 hours after admission.
  • No such associations were found in patients with cerebral hemorrhage admitted within 6 hours of stroke onset.

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