Increased Gut Microbial Translocation in HIV-infected Children Persists in Virologic Responders and Virologic Failures After Antiretroviral Therapy
The Pediatric Infectious Disease Journal, 06/01/2012
Pilakka–Kanthikeel S et al. – Microbial translocation (MT) persists after 44 weeks of antiretroviral therapy in VS and virologic failures (VF) patients. In VF, 16SrDNA exhibited relationships to monocyte and T cell IA and CD4 counts but not with viral load, suggesting a dominant role for MT in disease pathogenesis in HIV–infected children.