Sensing mechanisms involved in Ca2+ and Mg2+ homeostasis
Kidney International, 06/01/2012
Ferre S et al. – The tight coupling of the Calcium (Ca2+) and magnesium (Mg2+) homeostasis is frequently observed in humans and in animal models. Moreover, during the past decade, the intense research on mineral disorders, seen in the course of chronic kidney disease with secondary hyperparathyroidism, has revealed the interplay between Ca2+ and Mg2+ homeostasis. Altogether this evidence points to the CaSR as an interesting target to study mutual disturbances in Ca2+ and Mg2+ balance.