Use of Antidementia Drugs in Frontotemporal Lobar Degeneration
American Journal of Alzheimer's Disease and Other Dementias, 06/01/2012
Lopez–Pousa S et al. – There is a discrepancy regarding clinical practice and the recommendations based upon clinical evidence. The increased central nervous system drug use detected in frontotemporal lobar degeneration (FTLD) requires multicentric studies aiming at finding the best means to treat these patients.Methods
- Cross-sectional design using 1092 cases with Alzheimer’s disease (AD) and 64 cases with FTLD registered by the Registry of Dementias of Girona.
- Bivariate analyses were performed, and binary logistic regressions were used to detect variables associated with antidementia drugs consumption.
- The AChEIs were consumed by 57.6% and 42.2% of the patients with AD and FTLD, respectively.
- Memantine was used by 17.2% and 10.9% of patients with AD and FTLD, respectively.
- Binary logistic regressions yielded no associations with antidementia drugs consumption.