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Preoperative predictors for mortality following hip fracture surgery: A systematic review and meta-analysis
Injury, 05/14/2012
Hu F et al. – Whilst there is no conclusive evidence of the preoperative predictors for mortality following hip fractures, special attention should be paid to the above 12 strong evidence predictors.
Methods- Non–interventional studies were searched in Pubmed, Embase, Cochrane central database (all to February 26th, 2011).
- Only prospective studies and retrospective studies with prospective collected data were included.
- Qualities of included studies were assessed by a standardised scale previous reported for observational studies.
- The effects of individual studies were combined with the study quality score using a previous reported model of best–evidence synthesis.
- The hazard ratios of strong evidence predictors were combined only by high quality studies.
- 75 included studies with 94 publications involving 64,316 patients were included and the available observations was a heterogeneous group.
- The overall inpatient or 1month mortality was 13.3%, 3–6months was 15.8%, 1year 24.5% and 2years 34.5%.
- There were strong evidence for 12 predictors, including advanced age, male gender, nursing home or facility residence, poor preoperative walking capacity, poor activities of daily living, higher ASA grading, poor mental state, multiple comorbidities, dementia or cognitive impairment, diabetes, cancer and cardiac disease.
- The authors also identified 7 moderate evidence and 12 limited evidence mortality predictors, and only the race was identified as the conflicting evidence predictor.
