Can irradiation of potential cancer stem-cell niche in the subventricular zone influence survival in patients with newly diagnosed glioblastoma
Journal of Neuro-Oncology, 05/08/2012
Gupta T et al. – Multivariate analysis identified RPA class, Karnofsky performance status, and mean ipsilateral subventricular zones (SVZ) dose as independent predictors of survival. Increasing mean dose to the ipsilateral SVZ was associated with significantly improved OAS. Irradiation of potential cancer stem–cell niche influences survival outcomes in patients with newly diagnosed glioblastoma.