Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia

BMC Pediatrics, 04/26/2012

On basis of the derived population PK–PD models dosing guidelines will be developed for the application of drugs during neonatal hypothermia treatment. The results of this study will lead to an evidence based drug treatment of hypothermic neonatal patients. Results will be published in a national web based evidence based paediatric formulary, peer reviewed journals and international paediatric drug references.

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