The EuroChimerism concept for a standardized approach to chimerism analysis after allogeneic stem cell transplantation
Lion T et al. – The standardized STR–PCR tests permit detection of donor– or recipient–derived cells at a sensitivity ranging between 0.8 and 1.6%. Moreover, the EuroChimerism (EUC) assay facilitates accurate and reproducible quantification of donor and recipient hematopoietic cells. Wide use of the European–harmonized protocol for chimerism analysis presented will provide a basis for optimal diagnostic support and timely treatment decisions.