Mediterranean-style diet and risk of ischemic stroke, myocardial infarction, and vascular death: the Northern Manhattan Study Full Text
American Journal of Clinical Nutrition, 11/15/2011
Gardener H et al. – Higher consumption of a Mediterranean–style diet (MeDi) was associated with decreased risk of vascular events. Results support the role of a diet rich in fruit, vegetables, whole grains, fish, and olive oil in the promotion of ideal cardiovascular health.Methods
- The Northern Manhattan Study is a population–based cohort to determine stroke incidence and risk factors (mean ± SD age of participants: 69 ± 10 y; 64% women; 55% Hispanic, 21% white, and 24% black).
- Diet was assessed at baseline by using a food–frequency questionnaire in 2568 participants.
- A higher score on a 0–9 scale represented increased adherence to an MeDi.
- The relation between the MeDi score and risk of ischemic stroke, myocardial infarction (MI), and vascular death was assessed with Cox models, with control for sociodemographic and vascular risk factors.
- The MeDi–score distribution was as follows: 0–2 (14%), 3 (17%), 4 (22%), 5 (22%), and 6–9 (25%).
- Over a mean follow–up of 9 y, 518 vascular events accrued (171 ischemic strokes, 133 MIs, and 314 vascular deaths).
- The MeDi score was inversely associated with risk of the composite outcome of ischemic stroke, MI, or vascular death (P–trend = 0.04) and with vascular death specifically (P–trend = 0.02).
- Moderate and high MeDi scores were marginally associated with decreased risk of MI.
- There was no association with ischemic stroke.