Leukopenia as a risk factor for osteonecrosis of the jaw in metastatic prostate cancer treated using zoledronic acid and docetaxel

BJU International, 05/17/2012

Tooth extraction and nadir WBC counts <1000/μL were found to be risk factors for osteonecrosis of the jaw (ONJ) in metastatic prostate cancer treated with zoledronic acid and docetaxel combination therapy, showing that leukopenia is an important factor in the development of ONJ.

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