Maternal periodontitis as a risk factor for prematurity

Pediatrics International, 04/30/2012

Piscoya MDBV et al. – Periodontitis is strongly associated with prematurity, indicating necessity for regular periodontal investigation and treatment during pregnancy.


  • The authors carried out a case–control study including 718 puerperae who experienced a spontaneous delivery: 360 cases (premature) and 358 controls (full-term).
  • Sociodemographic, obstetric, prenatal, perinatal and periodontal data were obtained within 48 h after delivery.
  • Periodontitis was defined as probing depth >4 mm and attachment loss >3 mm at same site, for >4 teeth.


  • Periodontitis was associated with prematurity (odds ratio 6.95; confidence interval 3.69–13.09).
  • Prematurity was associated with maternal age < 20 years, family income < one minimum salary, maternal schooling < 8 years, premature birth history, premature membrane rupture, ruptured membranes > 24 h, smoking, urinary tract infection, leukorrhea, pre-eclampsia, prenatal consultations < 3 and precarious housing.
  • After multivariate confounder adjustments, periodontitis remained independently associated with prematurity (odds ratio 6.05; confidence interval 3.01–12.16).

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