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Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes

Morino K et al. – The data suggest that decreased mitochondrial content in muscle of insulin resistant (IR) offspring may be due in part to reductions in LPL expression in skeletal muscle resulting in decreased peroxisome proliferator–activated receptor (PPAR)–δ activation. [more...]

Diabetes

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