Parenteral vitamin D improves insulin sensitivity
As reported in Swiss Medical Weekly, supplemental vitamin D3 (300,000 IU im) in patients (n=55) with T2DM of > 10 y duration resulted in a 12.8% decrease in HOMA-IR at 6 months compared to an increase of 10% in patients who received placebo.
Increased prevalence of osteoporosis in morbidly obese
As reported in the International Journal of Clinical Practice, while there is a decreased prevalence of osteoporosis up to a BMI of 40 kg/m2, the prevalence of osteoporosis increases in patients with a BMI > 40 kg/m2, which is thought to be due to decreased weight-bearing exercise.
Pre-operative tranexamic acid reduces blood loss in ovarian cancer patients
As reported in ACTA Obstetricaet Gynecologica, a single pre-operative dose of tranexamic acid (15 mg/kg) significantly reduced blood loss (520 cc vs 730 cc) and the transfusion rate (30% vs. 44%) in ovarian cancer patients (n=100) undergoing radical debulking.