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Myoglobin Induces Vascular Cell Adhesion Molecule-1 Expression through c-Src Kinase-Activator Protein-1/Nuclear Factor-kB Pathways
Nephron: Experimental Nephrology, 11/03/09
Kim SH et al. – VCAM–1 expression via c–Src kinase–AP–1/NF–B pathways might be one of the possible mechanisms linking myoglobin to tubular injury. Losartan and simvastatin might be beneficial in attenuating myoglobin–induced tubular injury.
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