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Rottier BL et al. – In this heterogeneous group ICS or leukotriene receptor antagonists are just as effective as placebo; in the future it will hopefully be possible to describe characteristics of responders. LTRA are an alternative in mild asthma, especially when mono–triggered viral related wheeze is present. Theophylline is effective and also has bronchodilatory properties, which need to be balanced against the relatively frequent side effects. The working mechanisms of anti–inflammatory asthma medications including ICS, LTRA, cromones, macrolides and theophylline are described.

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