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Health State Values during the First Year of Drug Treatment in Early-Stage Parkinson's Disease: A Prospective, Population-Based, Cohort Study
Drugs & Aging, 10/26/09

Vossius C et al. – Patients with PD had lower SF–6D utility scores than controls at baseline. Patients started on antiparkinsonian drugs had an improvement in mean utility scores of 0.039 from 0.667 to 0.706. The ICER was €45 259 (2007 values) per QALY, of which two–thirds consisted of the costs of drugs and one–third represented the costs of clinical consultations. Drug treatment in patients with early–stage PD increases health state values, but the ICER is high. Further investigations will be necessary to capture the full consequences of treatment of PD and to evaluate the efficacy of disease management in this setting.

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Researchers identify genes associated with onset age of Parkinsons disease
EurekAlert, 10/08/09 Relevance Score: 80%

Serum uric acid levels in patients with Parkinson's disease: Their relationship to treatment and disease duration
Clinical Neurology and Neurosurgery, 10/07/09 Relevance Score: 80%

Deep brain stimulation as a new therapeutic approach in therapy-resistant mental disorders: ethical aspects of investigational treatment
European Archives of Psychiatry and Clinical Neuroscience, 11/10/09 Relevance Score: 79%

Calcium homeostasis, selective vulnerability and Parkinson's disease
Trends in Neurosciences, 10/05/09 Relevance Score: 79%

Cerebrospinal hypocretin, daytime sleepiness and sleep architecture in Parkinson's disease dementia
Brain, 10/30/09 Relevance Score: 70%