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Long-term cardiac follow-up of children treated with anthracycline doses of 300 mg/m2 or less for acute lymphoblastic leukemia
Pediatric Blood & Cancer, 10/29/09
Rathe M et al. – Anthracycline doses of <300 mg/m2 may contribute to a decline in cardiac function over time. Although the deterioration in cardiac parameters was not associated with clinical symptoms, life–long cardiac surveillance for these patients is important to establish the impact of low–dose anthracycline therapy on long–term cardiac health.
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