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Dotson K et al. – It is the goal in this review of the available literature on the use of IB, as an adjunct to inhaled short–acting beta–adrenergic agonists, to summarize practical, evidence–based recommendations for use in the pediatric emergency department setting for acute asthma exacerbations. The authors also hope to better delineate the most effective dosing regimen in those patients who might benefit most from the addition of IB and to explore proposed additional benefits it may have as a modulator of cholinergic–induced effects from high–dose beta–agonist therapy and viral triggers.

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