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Bronchial hyperreactivity in non-atopic children with asthma and reflux: Effect of anti-reflux treatment
Pediatric Pulmonology, 10/22/09
Khoshoo V et al. – Of the 21 patients positive for GERD (group A), 15 had positive MCT suggesting BHR. Of the 9 patients negative for GERD, 5 had positive MCT. On repeat testing 2 years later, 11/15 group A patients and 3/5 group B patients tested negative for BHR. Group A patients were receiving fewer asthma medications and experienced fewer exacerbations than Group B patients. BHR is prevalent in children with asthma and GERD and improves with anti–GERD treatment.
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