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Beta-catenin expression and claudin expression pattern as prognostic factors of prostatic cancer progression
BJU International, 10/14/09
Szasz AM et al. – The results suggest that patients with organ–confined and advanced cancer are subsets with distinct claudin expression profiles, and that claudin–4 is related to cellular differentiation in prostate cancer, which is not only the receptor molecule for the Clostridium perfringens enterotoxin, and thus a theoretical future therapeutic target for prostate cancer, but also a marker of progression.
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