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Review: diabetes is not a coronary disease equivalent
Evidence-Based Medicine, 10/06/09
Farkouh ME – Patients with diabetes and no history of myocardial infarction (MI) have a lower risk of coronary artery disease events than patients with previous MI and no diabetes.
Methods- Medline and EMBASE/Excerpta Medica (to Apr 2007); Cochrane Central Register of Controlled Trials; and references were searched for cohort studies involving 100 patients with follow–up 4 years. 13 articles reporting on 14 cohorts (n = 47 361, age 25–84 y, 0–100% men) met the selection criteria.
- Mean duration of follow–up was 13 years (range 5 to 25 y).
- Patients were enrolled at either a cross–sectional point in time (12 cohorts) or at diagnosis of diabetes or first MI (2 cohorts).
- Compared with patients with previous MI and no diabetes, those with diabetes and no MI had lower risk of a CAD event
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