Nursing Medical News about Disease Outbreaks Influenza A Virus, H1N1 Subtype

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The first Pandemic of the 21st Century: A Review of the 2009 Pandemic Variant Influenza A (H1N1) Virus
Postgraduate Medicine, 10/02/09

Scalera NM et al. – Swine influenza was first described in the 1918 pandemic and made a resurgence in April 2009 in the form of a triple–reassortant influenza A virus, which is composed of a combination of human, swine, and Eurasian avian strains. As evidenced with previous influenza pandemics, young adults and children aged < 24 years are the population most affected. Definitive diagnosis has largely been limited by the inability of conventional influenza testing to distinguish among influenza A subtypes; however, the surge in pandemic cases clearly emerged at the end of the annual influenza season in the northern hemisphere. The pandemic variant influenza A (H1N1) strain is typically susceptible to oseltamivir and resistant to adamantanes, unlike the 2008 to 2009 seasonal influenza A (H1N1). However, 2 cases of oseltamivir–resistant pandemic–variant influenza A (H1N1) were reported in late August 2009.

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Clinical and Epidemiologic Characteristics of an Outbreak of Novel H1N1 (Swine Origin) Influenza A Virus among United States Military Beneficiaries
Clinical Infectious Diseases, 11/16/09 Relevance Score: 98%

Notes from the Field: Outbreak of 2009 Pandemic Influenza A (H1N1) Virus at a Large Public University in Delaware, April–May 2009
Clinical Infectious Diseases, 11/16/09 Relevance Score: 98%

One Dose of H1N1 Vaccine Immunogenic in High Percentage of Pregnant Women. No Safety Concerns Reported During Ongoing Clinical Trial
American Family Physician, 11/06/09 Relevance Score: 97%

Novel Influenza A (H1N1) Outbreak at the U.S. Air Force Academy: Epidemiology and Viral Shedding Duration
American Journal of Preventive Medicine, 10/23/09 Relevance Score: 97%

Effectiveness and Cost-Effectiveness of Expanded Antiviral Prophylaxis and Adjuvanted Vaccination Strategies for an Influenza A (H5N1) Pandemic
Annals of Internal Medicine, 10/13/09 Relevance Score: 97%